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Hrvoje Brkić

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Hrvoje Brkić (* 17. September 1983 in Vinkovci) ist ein kroatischer Biophysiker.

Leben[Bearbeiten]

Er wurde in Vinkovci geboren, wo er die Grundschule und das Gymnasium Matija Antun Reljković besuchte. Im Jahr 2007 beendete er die Fakultät für Physik der J. J. Strossmayer-Universität Osijek und promovierte an der Naturwissenschaftlichen Fakultät in Zagreb. Dissertation mit dem Titel Computational Studies of Iron Dependent Dioxygenases, unter Mentor Prof. Dr. Sanja Tomić wurde 2014 verteidigt. Bis jetzt Co-Autor von ungefähr 30 international begutachteten wissenschaftlichen Arbeiten.

Derzeit ist er sowohl an der medizinischen Fakultät in Osijek als auch an der Fakultät für Zahnmedizin und Gesundheit beschäftigt, wo er in den Klassen medizinische Physik und Biophysik tätig ist.

Publikationen (Auswahl)[Bearbeiten]

  • Kopačin, Vjekoslav; Kasabašić, Mladen; Faj, Dario; de Saint Hubert, Marijke; Galić, Stipe; Ivković, Ana; Majer, Marija; Brkić, Hrvoje The Development of a computational pregnant female phantom and calculation of fetal dose during a photon breast radiotherapy. // Radiology and oncology (2022)
  • de Saint Hubert, Marijke; Tymińska, Katarzyna; Stolarczyk, Liliana; Brkić, Hrvoje Fetus dose calculation during proton therapy of pregnant phantoms using MCNPX and MCNP6.2 codes. // Radiation measurements, 149 (2021)[1]
  • Tomić, Antonija; Brkić, Hrvoje; Matić, Antonia; Tomić, Sanja Unravelling the inhibitory zinc ion binding site and the metal exchange mechanism in human DPP III. // PCCP. Physical chemistry chemical physics, 23 (2021)[2]
  • (EURADOS WG6) Rabus, Hans; Gomez-Ros, Jose-Maria; Villagrasa, Carmen; Eakins, Jonathan; Vrba, Tomas; Blideanu, Valentin; Zank, Maria; Tanner, Rick; Struelens, Lara; Brkić, Hrvoje et al. Quality assurance for the use of computational methods in dosimetry: activities of EURADOS Working Group 6 "Computational Dosimetry. // Journal of radiological protection, 41 (2021)[3]
  • Švabić Kolacio, Manda; Brkić, Hrvoje; Faj, Dario; Smilović Radojčić, Đeni; Rajlić, David; Obajdin; Nevena; Jurković, Slaven Validation of two calculation options built in Elekta Monaco Monte Carlo based algorithm using MCNP code. // Radiation physics and chemistry, 179 (2021)[4]
  • Ivković, Ana; Faj, Dario; Kasabašić, Mladen; Poje Sovilj, Marina; Krpan, Ivana; Grabar Branilović, Marina; Brkić, Hrvoje The influence of shielding reinforcement in a vault with limited dimensions on the neutron dose equivalent in vicinity of medical electron linear accelerator. // Radiology and oncology, 54 (2020)[5]
  • Brkić, Hrvoje; Kasabašić, Mladen; Ivković, Ana; Agić, Dejan; Krpan, Ivana; Faj, Dario Influence of head cover on the neutron dose equivalent in Monte Carlo simulations of high energy Medical linear accelerator. // Nuclear Technology & Radiation Protection, 33 (2018)[6]
  • Agić, Dejan; Brkić, Hrvoje; Tomić, Sanja; Karačić, Zrinka; Špoljarević, Marija; Lisjak, Miroslav; Bešlo, Drago; Abramić, Marija Validation of flavonoids as potential dipeptidyl peptidase III inhibitors: experimental and computational approach. // Chemical biology & drug design, 89 (2017)[7]
  • Brkić, Hrvoje; Ivković, Ana; Kasabašić, Mladen; Poje Sovilj, Marina; Jurković, Slaven; Štimac, Damir; Rubin, Otmar; Faj, Dario The influence of field size and off-axis distance on photoneutron spectra of the 18 MV Siemens Oncor linear accelerator beam. // Radiation measurements, 93 (2016)[8]
  • Brkić, Hrvoje; Kovačević, Borislav; Tomić, Sanja Human 3-hydroxyanthranilate 3, 4-dioxygenase (3HAO) dynamics and reaction, a multilevel computational study. // Molecular biosystems, 11 (2015)[9]
  • Istvanić, Tomislav; Vrselja, Zvonimir; Brkić, Hrvoje; Radić, Radivoje; Lekšan, Igor; Ćurić, Goran Extended Eversion Carotid Endarterectomy: Computation of Hemodynamics. // Annals of vascular surgery, 29 (2015)[10]
  • Brkić, Hrvoje Insight of the iron binding and transport in Dke1 - A Molecular Dynamics Study. // Croatica chemica acta, 88 (2015)[11]
  • Vrselja, Zvonimir; Brkić, Hrvoje; Mrđenović, Stefan; Radić, Radivoje; Ćurić, Goran Function of circle of Willis. // Journal of cerebral blood flow and metabolism, 34 (2014)[12]
  • Hrvoje, Brkić; Daniela, Buongiorno; Michael, Ramek; Grit, Straganz; Sanja, Tomić Dke1 – Structure, Dynamics and Function, A Theoretical and Experimental Study Elucidated the Role of the Binding Site Shape and the H-Bonding Network in Catalysis. // Journal of biological inorganic chemistry, 17 (2012)[13]
  • Rabus, Hans; Zankl, Maria; Gómez-Ros, José Maria; Villagrasa, Carmen; Eakins, Jonathan; Huet, Christelle; Brkić, Hrvoje; Tanner, Rick Lessons learnt from the recent EURADOS intercomparisons in computational dosimetry. // Radiation measurements (2022)[14]

Einzelnachweise[Bearbeiten]

  1. Marijke De Saint-Hubert, Katarzyna Tymińska, Liliana Stolarczyk, Hrvoje Brkić: Fetus dose calculation during proton therapy of pregnant phantoms using MCNPX and MCNP6.2 codes. In: Radiation Measurements. 149, 1. Dezember 2021, ISSN 1350-4487, S. 106665. doi:10.1016/j.radmeas.2021.106665.
  2. Antonija Tomić, Hrvoje Brkić, Antonia Matić, Sanja Tomić: Unravelling the inhibitory zinc ion binding site and the metal exchange mechanism in human DPP III. In: Physical Chemistry Chemical Physics. 23, 16. Juni 2021, ISSN 1463-9084, S. 13267–13275. doi:10.1039/D1CP01302E.
  3. H Rabus, J M Gómez-Ros, C Villagrasa, J Eakins: Quality assurance for the use of computational methods in dosimetry: activities of EURADOS Working Group 6 ‘Computational Dosimetry’. In: Journal of Radiological Protection. 41, 1. März 2021, ISSN 0952-4746, S. 46–58. doi:10.1088/1361-6498/abd914.
  4. Manda Švabić Kolacio, Hrvoje Brkić, Dario Faj, Đeni Smilović Radojčić: Validation of two calculation options built in Elekta Monaco Monte Carlo based algorithm using MCNP code. In: Radiation Physics and Chemistry. 179, 1. Februar 2021, ISSN 0969-806X, S. 109237. doi:10.1016/j.radphyschem.2020.109237.
  5. Ana Ivkovic, Dario Faj, Mladen Kasabasic, Marina Poje Sovilj: The influence of shielding reinforcement in a vault with limited dimensions on the neutron dose equivalent in vicinity of medical electron linear accelerator. In: Radiology and Oncology. 54, 1. Juni 2020, S. 247–252. doi:10.2478/raon-2020-0024. PMID 32374291.
  6. Hrvoje Brkić, Mladen Kasabašić, Ana Ivković, Dejan Agić: Influence of head cover on the neutron dose equivalent in Monte Carlo simulations of high energy medical linear accelerator. In: Nuclear Technology and Radiation Protection. 33, 2018, S. 217–222. doi:10.2298/ntrp1802217b.
  7. Dejan Agić, Hrvoje Brkić, Sanja Tomić, Zrinka Karačić: Validation of flavonoids as potential dipeptidyl peptidase III inhibitors: Experimental and computational approach. In: Chemical Biology & Drug Design. 89, S. 619–627. doi:10.1111/cbdd.12887.
  8. Hrvoje Brkić, Ana Ivković, Mladen Kasabašić, Marina Poje Sovilj: The influence of field size and off-axis distance on photoneutron spectra of the 18MV Siemens Oncor linear accelerator beam. In: Radiation Measurements. 93, ISSN 1350-4487, S. 28–34. doi:10.1016/j.radmeas.2016.07.002.
  9. H. Brkić, B. Kovačević, S. Tomić: Human 3-hydroxyanthranilate 3,4-dioxygenase (3HAO) dynamics and reaction, a multilevel computational study. In: Molecular BioSystems. 11, 17. Februar 2015, ISSN 1742-2051, S. 898–907. doi:10.1039/C4MB00668B.
  10. Tomislav Ištvanić, Zvonimir Vrselja, Hrvoje Brkić, Radivoje Radić: Extended Eversion Carotid Endarterectomy: Computation of Hemodynamics. In: Annals of Vascular Surgery. 29, 1. November 2015, ISSN 0890-5096, S. 1598–1605. doi:10.1016/j.avsg.2015.05.034.
  11. Hrvoje Brkić: Insight of the Iron Binding and Transport in Dke1 - A Molecular Dynamics Study. In: Croatica Chemica Acta. 88, 2015, ISSN 0011-1643, S. 297–306. doi:10.5562/cca2685.
  12. Zvonimir Vrselja, Hrvoje Brkic, Stefan Mrdenovic, Radivoje Radic: Function of Circle of Willis. In: Journal of Cerebral Blood Flow & Metabolism. 34, ISSN 0271-678X, S. 578–584. doi:10.1038/jcbfm.2014.7. PMID 24473483.
  13. Hrvoje Brkić, Daniela Buongiorno, Michael Ramek, Grit Straganz: Dke1—structure, dynamics, and function: a theoretical and experimental study elucidating the role of the binding site shape and the hydrogen-bonding network in catalysis. In: JBIC Journal of Biological Inorganic Chemistry. 17, 1. Juni 2012, ISSN 1432-1327, S. 801–815. doi:10.1007/s00775-012-0898-8.
  14. Hans Rabus, Maria Zankl, José Maria Gómez-Ros, Carmen Villagrasa: Lessons learnt from the recent EURADOS intercomparisons in computational dosimetry. In: Radiation Measurements. 156, 1. August 2022, ISSN 1350-4487, S. 106822. doi:10.1016/j.radmeas.2022.106822.


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